If the effect of a monster like "Malefic Blue-Eyes White Dragon" or "Malefic Red-Eyes B. Dragon" or "Malefic Stardust Dragon" is negated by an effect like "Skill Drain" or "Forbidden Chalice", then its effect "If there is no face-up Field Spell Card on the field, destroy this card." is also negated. Thus, "Malefic Blue-Eyes White Dragon" won't be destroyed if the Field Spell Card is removed from being face-up on the field.[6]
If "Skill Drain" is negating the effect "There can only be 1 face-up "Malefic" monster on the field." of a monster like "Malefic Blue-Eyes White Dragon" or "Malefic Red-Eyes B. Dragon" or "Malefic Stardust Dragon", then you still cannot Special Summon a second "Malefic Blue-Eyes White Dragon", since its effect is still active while it is in the hand.[7]